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Covid-19 information: UK to check one dose every of various covid-19 vaccines


A person wearing personal protective equipment holds a vaccine vial and syringe between their fingers

A physician prepares to manage the Pfizer/BioNTech covid-19 vaccine at a vaccination centre in Salisbury Cathedral in Salisbury, UK

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Newest coronavirus information as of 5pm on four February

UK plans to check impact of giving one dose every of the Pfizer and Astrazeneca covid-19 vaccines

A UK trial is aiming to analyze the affect of giving folks two completely different covid-19 vaccines for his or her first and second doses. Having the ability to use both vaccine will create extra flexibility within the supply of doses, and assist take care of disruption in provides, stated England’s deputy chief medical officer Jonathan Van-Tam. He stated combining two completely different vaccines on this means may additionally enhance immune responses, doubtlessly main to higher safety in opposition to covid-19. The trial, which is being led by researchers on the College of Oxford and funded by the UK authorities’s vaccine taskforce, will recruit 820 volunteers over the age of 50 who haven’t but obtained a covid-19 vaccine. Members will then obtain a primary dose of both the vaccine developed by the College of Oxford and AstraZeneca or the vaccine developed by Pfizer and BioNTech. A few of them will get the identical vaccine once more for his or her second dose 4 or 12 weeks later and others will get a second dose of the opposite vaccine, to check the impact of mixing the 2 pictures and of various time intervals between doses.

UK vaccines minister Nadhim Zahawi stated the nation is on monitor to satisfy its goal of vaccinating all folks within the 4 precedence teams in opposition to covid-19 by 15 February. He informed parliament it has been “an unimaginable effort” that has “drawn on the exhausting work of so many”. Final month, UK Prime Minister Boris Johnson stated the UK authorities goals to have given a primary dose of covid-19 vaccine to all these over 70, probably the most clinically susceptible folks and frontline well being and social care staff by 15 February – equal to about 15 million folks. Throughout the UK, greater than 10.four million folks had obtained a primary dose of covid-19 vaccine as of four February.

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Different coronavirus information

Worldwide journey was related to elevated loss of life charges within the worst-affected nations in the course of the first wave of the coronavirus pandemic, in response to a research printed within the scientific journal BMJ Open. Tiberiu Pana on the College of Aberdeen, UK, and colleagues analysed the connection between country-level components – reminiscent of worldwide arrivals, inhabitants density and well being indicators – and the common enhance in day by day deaths recorded in early 2020 throughout the 37 nations with the very best loss of life charges from covid-19. They discovered that the largest enhance in loss of life charges was related to worldwide arrivals. A rise of one million worldwide arrivals was related to a 3.four per cent rise within the common day by day enhance in covid-19 deaths.

A World Well being Group scientist has stated society is unlikely to return to “regular” till 2022. “I feel we’re going to be effectively into subsequent 12 months earlier than we see a change – that change is more likely to be brought on by excessive protection of the vaccines,” stated Helen Rees, who sits on the WHO’s committee for covid-19. “I feel this new regular all of us speak about is with us for a really very long time,” Rees informed BBC Wales Stay.

Coronavirus deaths

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The worldwide covid-19 loss of life toll has handed 2.27 million. The variety of confirmed instances is greater than 104 million, in response to Johns Hopkins College, although the true variety of instances can be a lot increased.

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The New York Occasions is monitoring hospital mattress occupancy in England in an interactive graphic.

Panorama: The Race for a Vaccine is a BBC documentary concerning the inside story of the event of the Oxford/AstraZeneca vaccine in opposition to covid-19.

Race Towards the Virus: Hunt for a Vaccine is a Channel four documentary which tells the story of the coronavirus pandemic by way of the eyes of the scientists on the frontline.

The New York Occasions is assessing the progress of various vaccine candidates and potential drug remedies for covid-19, and rating them for effectiveness and security.

People of COVID-19 is a undertaking highlighting the experiences of key staff on the frontline within the struggle in opposition to coronavirus within the UK, by way of social media.

Stomach Mujinga: Looking for the Reality is a BBC Panorama investigation of the loss of life of transport employee Stomach Mujinga from covid-19, following studies she had been coughed and spat on by a buyer at London’s Victoria Station.

Coronavirus, Defined on Netflix is a brief documentary sequence analyzing the on-going coronavirus pandemic, the efforts to struggle it and methods to handle its psychological well being toll.

New Scientist Weekly options updates and evaluation on the newest developments within the covid-19 pandemic. Our podcast sees knowledgeable journalists from the journal talk about the largest science tales to hit the headlines every week – from expertise and house, to well being and the atmosphere.

COVID-19: The Pandemic that By no means Ought to Have Occurred, and Learn how to Cease the Subsequent One by Debora Mackenzie is about how the pandemic occurred and why it can occur once more if we don’t do issues in another way in future.

The Guidelines of Contagionis concerning the new science of contagion and the stunning methods it shapes our lives and behavior. The writer, Adam Kucharski, is an epidemiologist on the London College of Hygiene and Tropical Medication, UK, and within the ebook he examines how ailments unfold and why they cease.

Earlier updates

Royal Navy medics prepare syringes of the Oxford/AstraZeneca covid-19 vaccine at a vaccination centre

Royal Navy medics put together syringes of the Oxford/AstraZeneca covid-19 vaccine at a vaccination centre in Bathtub, UK

ADRIAN DENNIS/AFP by way of Getty Photos

Three February

Covid-19 vaccine in opposition to new variants may very well be deployed quickly, says Oxford vaccine researcher

A model of the covid-19 vaccine developed by the College of Oxford and AstraZeneca that may deal with the brand new, extremely transmissible coronavirus variants may very well be able to deploy in about 7 months within the UK, in response to a researcher on the Oxford vaccine group. “The precise work on designing a brand new vaccine could be very, very fast as a result of it’s basically simply switching out the genetic sequence for the spike protein,” Andrew Pollard on the College of Oxford informed the BBC. “After which there’s manufacturing to do after which a small scale research. So all of that may be accomplished in a really quick time frame, and the autumn is admittedly the timing for having new vaccines obtainable to be used,” he stated. Pollard stated work is already underway to replace the vaccine and enhance its efficacy in opposition to not too long ago recognized coronavirus mutations, reminiscent of these within the variants first sequenced within the UK and South Africa.

Preliminary outcomes recommend that the Oxford/AstraZeneca vaccine might scale back coronavirus transmission, along with decreasing symptomatic covid-19 and extreme sickness. UK well being minister Matt Hancock praised the findings of the research led by researchers on the College of Oxford. The outcomes point out that two doses of the jab scale back coronavirus an infection with or with out signs by 67 per cent. In addition they recommend {that a} single dose of the vaccine is 76 per cent efficient at stopping symptomatic covid-19 for 3 months, with this determine growing to 82 per cent after two doses. Hancock described the outcomes as “completely very good” and stated they present that “vaccines are the way in which out of this pandemic”.

Different coronavirus information

A cell coronavirus testing unit has been arrange within the city of Southport in England to check residents for the coronavirus and establish if they’ve the variant first recognized in South Africa. Firefighters and council workers are additionally delivering 10,000 house testing kits to folks dwelling within the space.

Denmark introduced plans to introduce a digital “Corona-Move”, which might permit Danish residents to show they’ve been vaccinated in opposition to covid-19 for the needs of enterprise and leisure journey, in response to the nation’s finance ministry.

Israel will begin increasing its covid-19 vaccination programme to everybody over the age of 16, in response to its well being ministry.

Coronavirus deaths

New Scientist Default Image

The worldwide covid-19 loss of life toll has handed 2.25 million. The variety of confirmed instances is greater than 104 million, in response to Johns Hopkins College, although the true variety of instances can be a lot increased.

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Passengers push luggage on trolleys through a terminal at London's Heathrow airport

Travellers arrive at London’s Heathrow airport

Hollie Adams/Getty Photos

2 February

UK science advisers advisable introduction of journey restrictions two weeks in the past

The UK’s Scientific Advisory Group for Emergencies (SAGE) suggested the federal government to introduce obligatory lodge quarantine for travellers arriving into the UK two weeks in the past, in response to minutes from a gathering on 21 January that had been leaked to the Occasions. On Thursday 21 January, SAGE reportedly warned that “reactive, geographically focused” journey bans couldn’t be relied on to forestall faster-spreading coronavirus variants, reminiscent of these recognized in South Africa and Brazil, from reaching the UK, including that: “no intervention, apart from an entire, pre-emptive closure of borders, or the obligatory quarantine of all guests upon arrival in designated services, regardless of testing historical past, can get shut to totally stopping the importation of recent instances or new variants.”

A Downing Road spokesperson stated SAGE didn’t immediately advise UK prime minister Boris Johnson to shut borders. Universities minister Michelle Donelan informed Sky Information that the federal government “at all times primarily based our selections on the perfect medical and scientific recommendation” and stated “the SAGE recommendation really stated it could most likely be ineffective, actually, to shut the borders, which was the identical recommendation that we bought on the time from the World Well being Group”. Johnson introduced geographically focused lodge quarantine measures for travellers getting back from 30 nations, together with Brazil and South Africa, final week.

UK well being minister Matt Hancock urged folks dwelling in postcodes in England singled out for enhanced coronavirus testing for the so-called South Africa variant to keep at house until “completely important”. Pressing door-to-door testing for the faster-spreading variant has been deployed after 11 instances with no hyperlink to international journey had been recognized in elements of England.

Different coronavirus information

Interim outcomes from section III trials recommend Russia’s covid-19 vaccine is 91.6 per cent efficient, and knowledge on the vaccine is being submitted to the European Medicines Company, in response to Kirill Dmitriev, director of the Russian Direct Funding Fund. The outcomes, primarily based on a section III trial together with 21,977 adults, three-quarters of whom obtained the Sputnik V vaccine, are printed in scientific journal the Lancet. Different members obtained a placebo.

Sweden introduced it could not advocate the covid-19 vaccine developed by the College of Oxford in partnership with AstraZeneca for folks aged over 65, hours after Poland stated it could not supply the vaccine to over 60s. Final week, medical consultants in Germany and Austria made comparable suggestions, citing a scarcity of information on this age group. The European Medicines Company authorised the vaccine to be used in all grownup age teams throughout the European Union and June Raine, chief government of the UK Medicines and Healthcare merchandise Regulatory Company, final week stated: “Present proof doesn’t recommend any lack of safety in opposition to covid-19 in folks aged 65 or over. The information now we have exhibits that the vaccine produces a powerful immune response within the over-65s.”

Coronavirus deaths

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The worldwide covid-19 loss of life toll has handed 2.24 million. The variety of confirmed instances is greater than 103 million, in response to Johns Hopkins College, although the true variety of instances can be a lot increased.

Newest on coronavirus from New Scientist

Sooner-spreading variants: The faster-spreading UK coronavirus variant has acquired a mutation that may assist it evade immune safety – the identical mutation already discovered within the South African variant.

A health worker talks with a man taking a swab test in a park

A well being employee talks with a person taking a swab check in Goldsworth Park, because the South African variant of the novel coronavirus is reported in elements of Surrey, in Woking, UK, 1 February 2021

REUTERS/Hannah McKay

1 February

All adults in elements of England to be examined for South Africa variant after 11 new instances recognized

Door-to-door testing for the so-called South Africa coronavirus variant will start in elements of England this week, after 11 instances with no recognized hyperlinks to journey or to earlier instances had been recognized in eight areas of the nation. Pressing testing of adults, no matter signs, will happen in some postcodes in Hertfordshire, Surrey, Kent, Walsall, Sefton and within the London boroughs of Merton, Haringey and Ealing. “We try to include this so it doesn’t unfold,” Susan Hopkins, senior medical adviser at Public Well being England informed the BBC. Any newly recognized infections can be analysed to see if they’re brought on by the extremely transmissible coronavirus variant first sequenced in South Africa.

UK well being minister Matt Hancock “has ordered an try at eradication of the brand new variant if in any respect potential”, with public well being officers beginning to go door-to-door in affected areas this week, in response to a briefing seen by the Guardian. “It is a precautionary measure,” stated Ruth Hutchinson, director of public well being for Surrey, in a press release. “The extra instances of the variant we discover, the higher probability now we have at stopping it from spreading additional,” stated Hutchinson, including: “It’s actually essential to say that there’s at the moment no proof that this variant causes extra extreme sickness, so that you don’t want to fret.”

Different coronavirus information

A covid-19 vaccine has now been provided to older residents at each eligible care house in England, the NHS introduced, however vaccination charges of care house workers are lagging behind residents. Fiona Carragher, director of analysis and influencing at Alzheimer’s Society informed the BBC she remained involved that the vaccination rollout for care house workers “has not been almost so efficient”. In January, UK Prime Minister Boris Johnson stated the UK authorities goals to vaccinate all these over 70, probably the most clinically susceptible folks and frontline well being and social care staff by 15 February – equal to about 15 million vaccinations. Throughout the UK, greater than 8.9 million folks had obtained a primary dose of covid-19 vaccine as of 30 January.

The European Union stated AstraZeneca has agreed to produce it with 9 million further doses of its covid-19 vaccine, developed in partnership with the College of Oxford. This brings the overall variety of anticipated doses for the primary quarter of this 12 months to 40 million, which is about half of what the EU was initially anticipating. European Fee president Ursula von der Leyen tweeted saying the corporate would broaden its manufacturing capability in Europe, and begin delivering doses every week sooner than scheduled.

Germany’s well being minister Jens Spahn hinted that covid-19 vaccines from China and Russia may very well be utilized in Europe to compensate for the shortfall of doses equipped by Pfizer and its accomplice BioNTech, and by Oxford/AstraZeneca. “Whatever the nation through which a vaccine is manufactured, if they’re secure and efficient, they might help deal with the pandemic,” Spahn informed German media on Sunday, including that any vaccine will first should be authorized by the European Medicines Company.

Coronavirus deaths

New Scientist Default Image

The worldwide covid-19 loss of life toll has handed 2.23 million. The variety of confirmed instances is greater than 103 million, in response to Johns Hopkins College, although the true variety of instances can be a lot increased.

Newest on coronavirus from New Scientist

Can vaccines cease transmission?: A number of research recommend that coronavirus vaccines can considerably scale back transmission of the virus, however not halt it utterly – so social distancing remains to be crucial.

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A lab technician working at Janssen Pharmaceutical in Beerse, Belgium

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29 January

Vaccines from Johnson & Johnson and Novavax report constructive trial outcomes

A coronavirus vaccine developed by the US agency Novavax has been proven to be 89 per cent efficient in stopping covid-19 in medical trials. The trials included members within the UK and South Africa, and located the vaccine to be 86 per cent efficient in opposition to the UK variant of the virus, however solely 60 per cent efficient in opposition to the variant in South Africa. Novavax stated it can instantly start improvement on a vaccine particularly focused to the South African variant.

Janssen, a subsidiary of US agency Johnson & Johnson, introduced that its covid-19 vaccine confirmed 66 per cent efficacy in a world trial. These outcomes are primarily based on a single dose of the vaccine, which makes it simpler to manage than the two-shot vaccines which have already been authorized. The corporate has stated it can promote its vaccine on a not-for-profit foundation.

The UK has already ordered 30 million doses of the Janssen vaccine and the European Union has ordered 400 million. The UK has additionally ordered 60 million doses of the Novavax jab.

Different coronavirus information

The European Medicines Company has advisable the approval of the Oxford/AstraZeneca coronavirus vaccine for all adults, which is able to permit mass use of the vaccine within the European Union. Yesterday, a German committee advisable in opposition to approving the vaccine for folks over 65 due to inadequate knowledge within the trials, however the EMA’s consultants stated safety may very well be anticipated on this group and there’s dependable data on security. The vaccine is already the topic of a dispute between AstraZeneca and the EU over the agency’s choice to produce fewer doses to the EU this 12 months than initially agreed. Right now, the European Fee printed elements of its contract with AstraZeneca, which it says obliges the corporate to produce the agreed volumes. The drug-maker says the contract solely obliges it to make its “greatest effort” to satisfy the EU demand, to not stick with a particular timetable. The EU additionally introduced export restrictions on vaccines made inside the bloc in response to the deliberate reduce in deliveries.

The coronavirus variant from South Africa – which is extra infectiousness than the unique variant has been detected within the US for the primary time, with two instances confirmed in South Carolina.

The New York state authorities has launched new figures exhibiting that it undercounted deaths from covid-19 in nursing house residents by greater than 3800. The state’s general loss of life toll has not elevated, however the increased tally in nursing properties has fuelled criticism that governor Andrew Cuomo didn’t do sufficient to guard these residents.

Within the UK, covid-19 hospital admissions fell to 33.51 per 100,000 folks from a price of 35.64 within the week ending 24 January, figures from the Workplace for Nationwide Statistics present. One in 55 folks in non-public households in England examined constructive for covid-19 between 17 and 23 January, which has similarities to the earlier week. The an infection price was roughly one in 70 in Wales, one in 50 in Northern Eire and one in 110 in Scotland. The R quantity for the UK is between 0.7 and 1.1, in response to the newest estimate by the federal government’s scientific advisory group. The R quantity is the variety of folks every individual with covid-19 will go on to contaminate.

Newest on coronavirus from New Scientist

World vaccine distribution: Whereas mass immunisation programmes are making speedy progress in wealthy nations, many middle-income nations have solely simply begun roll-outs and most low-income ones will take months to get began. These delays enhance the danger of mutations resulting in variants which are extra transmissible,and will render vaccines much less efficient in future.

Coronavirus deaths

The worldwide covid-19 loss of life toll has handed 2.19 million. The variety of confirmed instances is greater than 101 million, in response to Johns Hopkins College, although the true variety of instances can be a lot increased.

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