Why are SARS-CoV-2 an infection charges and COVID-19 hospitalizations dropping so quickly nowadays within the U.S.? A 2/17/21 story by Derek Thompson at The Atlantic stories that it’s a mixture of higher social distancing, elevated mask-wearing, seasonality, a rising variety of individuals within the U.S. who’ve developed antibodies after an infection with the virus (15% to 30% of U.S. adults), and the rising variety of individuals within the U.S. who’ve been vaccinated in opposition to COVID-19. “We’re accelerating towards a second, someday this spring, when half of American adults ought to have some sort of coronavirus safety,” Thompson concludes.
For a fast dive into key outcomes from large-scale COVID-19 vaccine research carried out by Pfizer/BioNTech, Moderna, AstraZeneca, Novavax, Johnson and Johnson, and Gamaleya Sputnik V, see Yale College immunologist Akiko Iwasaki’s 2/7/21 Twitter thread that includes comparative tables, made by Yale Medical College college students. “All of the tables right here…point out the # COVID-related loss of life within the vaccinated because the right-most column (which is ZERO).” She provides: “With all these vaccines…we are able to deliver down the variety of extreme & deadly Covid. The variants are right here, however present vaccines nonetheless shield from extreme illness & vaccines for the variants are coming. We are going to get by way of this!”
A 2/16/21 story by Ariana Remmel for Nature contains bar charts that illustrate the frequency of unwanted side effects reported to the U.S. Facilities for Illness Management amongst individuals who have acquired the Pfizer/BioNTech vaccine in opposition to COVID-19. The chart exhibits that fatigue is reported by 29% and 50% of individuals receiving their first- and second-dose, respectively; complications are reported by 26% and 42% of individuals receiving their first- and second-dose, respectively; and fever is reported by 7% and 25% of individuals receiving their first- and second-dose, respectively. Individuals report extra unwanted side effects to this vaccine and to Moderna’s COVID-19 vaccine than they do to flu vaccines, based on an infectious-disease specialist on the College of Washington College of Drugs, the story states. The piece additionally states that the frequency of anaphylactic (extreme, allergic, and life-threatening) reactions to the Moderna vaccine is three per million doses, and it’s 30 per three million doses thus far for the Oxford-AstraZeneca vaccine. All these people have “absolutely recovered,” per the story. Anaphylaxis is treatable if caught shortly, based on Paul Offit, a vaccine specialist at Kids’s Hospital of Philadelphia who’s quoted within the story. Remmel writes: “There isn’t any query that the present vaccines are efficient and secure. The danger of extreme response to a COVID-19 jab, say researchers, is outweighed by the safety it gives in opposition to the lethal coronavirus.”
Epidemiologist Katelyn Jetelina of the College of Texas Well being Science Middle at Houston printed a 2/14/21 submit at her Your Native Epidemiologist web site that summarizes the most recent proof for medicine to deal with COVID-19. The submit relies on a 280-page report on COVID-19 therapy choices printed 2/11/21 by the U.S. Nationwide Institutes of Well being. Two choices proven by research to work thus far: steroids known as corticosteroids (particularly, they shield in opposition to loss of life from extreme COVID-19 and reduce how lengthy you must keep in an intensive care unit), and the anti-viral drug remdesivir (it’s protecting for hospitalized sufferers who want supplemental oxygen, apart from ventilators). The submit features a 12/10/20 chart printed within the British Medical Journal that summarizes the experimental outcomes of lots of the medicine examined in opposition to COVID-19. The submit additionally summarizes the proof for “medicine which might be making headlines,” nevertheless it suggests there presently isn’t sufficient proof to help giving them to COVID-19 sufferers (e.g. ivermectin, arthritis drug tocilizumab, and bronchial asthma drug budesonide).
COVID-19 might need humbled Peter Diamandis, entrepreneur and founding father of the X Prize Basis, he suggests in a 2/12/21 weblog submit. Takeaway: regardless of high-quality pre-arrival and day by day testing, a gathering of what feels like about 100 individuals for a convention become a superspreader occasion that contaminated a few quarter of attendees. A gaggle of audiovisual and manufacturing technicians who saved to themselves and reportedly wore masks all through the occasion was spared. Diamandis writes: “Masks Work.”
The “bona fide nerdy women” at Pricey Pandemic (particularly, they’re an interdisciplinary all-female crew of researchers and clinicians who work in nursing, well being coverage, and epidemiology amongst different fields) at the moment are publishing Spanish-language COVID-19 info at a Fb web page known as Querida Pandemia.
The UnbiasedSciPod, a podcast co-hosted by Jessica Steier, a public well being researcher and information scientist, and Andrea Love, an immunologist and microbiologist, posts some useful graphics at its Instagram web page, together with this one on 2/11/21 displaying up to date U.S. Facilities for Illness Management suggestions that pertain to individuals who’ve been vaccinated and later uncovered to somebody considered contaminated with SARS-CoV-2 or to have COVID-19. In case you fall inside two-weeks and three months of receiving your remaining vaccine dose and don’t have any signs following contact with somebody who has the virus or COVID-19, you now not are required to quarantine, per the submit. However you continue to “should proceed sporting a masks and working towards social distancing,” it states.
You may get pleasure from “I’ve by no means tried your concept, and now every part is on hearth, and that’s how I do know your concept is unhealthy,” by Eli Grober (1/17/21) in McSweeney’s.
That is an opinion and evaluation article.